Cancer Genomics

RNA Polymerase II at histone genes predicts outcome in human cancer

We demonstrate that RNA Polymerase II occupancy at histone genes, measured by FFPE-CUTAC, serves as a powerful predictor of cancer outcomes and enables efficient tumor classification.

Henikoff S, Zheng Y , Paranal R, Xu Y, Greene J, Henikoff J, Russell Z, Szulzewsky F, Thirimanne H, Kugel S, Holland E, Ahmad K

Mitotic errors do not explain aneuploidy in cancer

Henikoff S, Zheng Y , Ahmad K