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Computational Biology
scGAD: single-cell gene associating domain scores for exploratory analysis of scHi-C data
Quantitative tools are needed to leverage the unprecedented resolution of single-cell high-throughput chromatin conformation (scHi-C) …
Shen S,
Zheng Y
, Keles S
Project
DOI
Paper
Normalization and de-noising of single-cell Hi-C data with BandNorm and scVI-3D
Single-cell high-throughput chromatin conformation capture methodologies (scHi-C) enable profiling of long-range genomic interactions. …
Zheng Y
, Shen S
, Keles S
Project
DOI
Paper
FreeHi-C Spike-in Simulations for Benchmarking Differential Chromatin Interaction Detection
High-throughput genome-wide chromatin conformation capture assay (Hi-C) is routinely used to profile long-range genomic interactions …
Zheng Y
, Zhou P, Keles S
Project
DOI
Paper
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